1.Yintoni iPregabalin?

Pregabalin (I-148553-50-8) sisiyobisi esona sithengiswa kakhulu phantsi kwegama lophawu u-Lyrica kwimimandla eyahlukeneyo yehlabathi. Ngaba liyeza elichasene ne-epileptic ekwabizwa ngokuba yi-anticonvulsant. Eli chiza lisetyenziselwa ukunciphisa isantya sobuchopho esikhokelela ekubanjweni. Kwelinye icala, iPregabalin ichaphazela iikhemikhali zobuchopho ezithumela imiqondiso yeentlungu kuyo yonke imithambo-luvo yomzimba. Eli chiza likwasetyenziswa kwilizwe lonyango ukunyanga iintlungu ezahlukeneyo ezibangelwa zizifo ezahlukeneyo ezinjengentlungu yentliziyo ebangelwa yi-fibromyalgia, isifo seswekile, kunye nentlungu yomonzakalo wentambo.

I-Pregabalin ikhona iicaphule, eyandisiweyo-ekhutshwayo, okanye iitafile ezinde kunye nokwenza isisombululo somlomo (ulwelo). Zonke iifom zePregabalin zisebenza ngendlela efanayo, kwaye ugqirha wakho uya kuba ngoyena mntu uza kukhetha eyona ilungileyo kuwe ngokuxhomekeke kwimeko yakho okanye kwinto oyifunayo ukuyiphumeza kumjikelo wethamo. Ukuba sisiyobisi somlomo sisebenza njengelona chiza lihle kakhulu kwizigulana ezininzi ezingaguqukiyo ngenaliti eliqhelekileyo. Ichiza likwanokukhokelela kwezinye iziphumo ezibi xa usela kakhulu okanye usetyenziswa gwenxa. Qiniseka ukuba uhlala ulandela imiyalelo yedosi yeziphumo ezingcono.

I-Pregabalin (148553-50-8) inokusetyenziswa kunye namanye amayeza ukunceda unyango lokuthathwa kwesi sifo kubantwana abaneminyaka yobudala emi-4 kunye nabantu abadala nabo. Kwiminyaka emininzi ngoku, eli chiza belidlala indima ebalulekileyo kwilizwe lezonyango, lisenza libe lelona chiza linamandla lokunciphisa iintlungu kwintengiso. Iyeza kufuneka lithathwe kuphela phantsi kokuyalelwa ngugqirha ukufumana iziphumo ezingcono. Nangona kunjalo, uhlala uqinisekisa ukuba ufumana iPregabalin kumthengisi othembekileyo okanye umenzi ojikelezileyo.

2.Indlela yokusebenza yePregabalin

I-Pregabalin yodidi lwama-anticonvulsants amayeza. Ngokwesiqhelo, amachiza akweliklasi asebenza ngendlela efanayo kwaye asetyenziswa kunyango lweemeko ezifanayo. Akukacaci ukuba isebenza njani kanye le Pregabalin, kodwa kukholelwa ukuba isebenze ngokuzola iintlungu ezonakeleyo emzimbeni ezikhokelela ekubambeni okanye kubuhlungu. Ichiza linciphisa iintlungu emzimbeni ezibangelwa zizizathu okanye izifo ezahlukeneyo. Thetha ugqirha wakho ngolwazi oluthe kratya malunga nePregabalin.

3.Ukusetyenziswa kwePregabalin

E-United States yaseMelika, iPregabalin ivunyiwe ukuba isetyenziswe kunyango lwezifo ezifana;

  • sokuwa
  • I-post-herpetic neuralgia okanye iintlungu ezivela emva kokuncipha
  • Isifo se-neuropathy yesifo seswekile kunye
  • Fibromyalgia

I-Fibromyalgia yimeko yempilo ebandakanya iintlungu ezixhaphakileyo, njengezihlunu, izicubu ezinxibelelanayo, okanye ukuphakama okuphezulu kunye nokuphendula okubuhlungu ekuchukumiseni. Kweminye imimandla yehlabathi, njengaseYurophu, iPregabalin isetyenziswa kunyango lwexhala, imeko eliza kusetyenziswa ngamanye amayeza ukunyanga eUnited States yaseMelika. Njengoko kuchaziwe ngaphambili, iPregabalin ikwasetyenziswa namanye amachiza ukuphucula iziphumo. Oogqirha banokukunika amayeza kwizigulana ezineemeko ezahlukeneyo ezinokunyangwa okanye zilawulwe yiPregabalin.

Yonke into omele uyazi ngePregabalin

4.Umthamo wePregabalin

Idosi ye-Pregabalin ixhomekeke kwimeko phantsi konyango. Nangona kunjalo, owona umthamo uphantsi yi-25mg, ngelixa elona xabiso liphezulu yi-600mg ngosuku. Ugqirha wakho uza kukuseza umthamo ofanelekileyo emva kokuvavanya imeko yakho. Ngamanye amaxesha ii-medics ziya kukucebisa ukuba uqale ngeedosi ezisezantsi, ezinokulungiswa kunye nexesha. Kwezinye iimeko ezikhethekileyo, ugqirha wakho unokunyusa umthamo ngakumbi. I Umthamo wePregabalin zezi zilandelayo;

Unyango lwabantu abadala Iswekile ye-Neuropathy

Ukukhutshwa kwangoko, idosi yokuqala yi-50mgs ekufuneka ithathwe kathathu ngemini. Idosi inokonyulwa ngugqirha wakho ukuya kwi-100mg ukuba ithathwe kathathu ngemini kwiveki yokuqala, eya kuthi igqitywe yindlela umzimba wakho ophendula ngayo kwidosi yokuqala. Uvavanyo lonyango lubalulekile ukubeka iliso kwinkqubela phambili yonyango. Okwangoku, umthamo we-Pregabalin ungathatyathwa ubude be-300mg ngemini, kodwa oko kufuneka kwenziwe ngexesha. Abaqalayo bahlala becetyiswa ukuba baqalise ngeedosi ezisezantsi ukunciphisa iziphumo ebezingalindelekanga.

Ukukhutshwa okwandisiweyo kuya kufuna ukuba uthathe umthamo wokuqala we-150mg idosi yomlomo kanye ngemini, kwaye kuyacetyiswa ukuba uyithathe emva kwesidlo sangokuhlwa. Ugqirha wakho unokunyusa umthamo ukuya kufikelela kweyona nqanaba liphezulu ye-330mg yonke imihla. Ukonyuswa komthamo kunokwenzeka kuphela emva kokuba ugqirha evavanye inkqubela yakho kunye nokunyamezelana komzimba wakho kuPregabalin. Khumbula, musa ukuhlengahlengisa iPregabalin (148553-50-8) ithamo ngaphandle koncedo lukagqirha. Ingakhokelela kwiziphumo ezibi kakhulu.

Umhla oya kutshintshwa ngawo umthamo thatha imilinganiselo yentsasa yesiqhelo njengoko kumiselwe ngamayeza akho emva koko uqale ithamo elitsha emva kwesidlo sakho sangokuhlwa. Izifundo zonyango zityhile ukuba ukuthatha imithamo ephezulu ukuya kuthi ga kwi-600mg ngemini akuniki zibonelelo zongezelelweyo. Ke, kuya kufuneka unamathele kwidosi ecetyiswayo. Ukuthatha i-300 ephezulu ukuya kwi-330gm ngosuku nayo ayikacetyiswa kuba inokukhokelela kwimiphumo yokuxhomekeka kwidosi.

I-Postherpetic Neuralgia idosi yabantu abadala

Apha iithamo zahlulahlulwe zangumacandelo amabini, ukukhutshwa kwangoko, kunye nokukhutshwa okwandisiweyo, kwaye zombini zahlukile kwiidosi. Umzekelo, ukukhutshwa kwangoko, idosi yokuqala yePregabalin yi-150mg ukuya kwi-300mg ngemini, eyahlulwe kubini okanye kathathu ngemiyalelo ngosuku. Ngokufanayo, iidosi zonyuswa ziye kwi-300 ngosuku emva kweentsuku ezimbalwa kuxhomekeka kwindlela umzimba wakho ophendula ngayo kwidosi yokuqala. Ukuba iziphumo zinomdla, ke ugqirha akasayi kuba nasizathu sokuyonyusa. Amayeza anokuthoba umthamo ngakumbi ukuba uthatha imithamo ephantsi kwaye uneziphumo ezibi kakhulu.

Emva kokuthatha i-300mg dosage malunga neeveki ezimbini ukuya kwezine, kwaye ukukhululeka kwentlungu akwanele, ugqirha unokuthatha isigqibo sokuyinyusa malunga ne-600mgs imihla ngemihla ukuba ithathwe kabini okanye kathathu ngemini. Khumbula, i-600mg ngosuku lelona lilo liphezulu lonyuswe kakhulu kuzo zonke izigulana. Ukugqwesa kweli nqanaba kunokukhokelela kwiziphumo ezibi zePregabalin, eya kuba nzima okanye ibe yindleko ukubuyisela umva.

Ukukhutshwa okwandisiweyo:

Apha, umthamo wokuqala wePregabalin yi-165mg ekufuneka ithathwe kanye ngosuku, kwaye kuyacetyiswa ukuba uyithathe emva kwesidlo sangokuhlwa. Kukho amathuba okuba umthamo wonyuswe uye kwi-330mg kwiveki yokuqala yomjikelo wethamo. Emva kweeveki ezimbini okanye iiveki zonyango kwaye akukho phuculo lubalulekileyo kwiinhlungu emva koko ugqirha wakho unokuphakamisa umthamo ukuba uphezulu kangakanani i-660mgs ngemini. Xa utshintsha imithamo, thabatha ekuseni ukuze ukhuphe ngokukhawuleza emva koko uqalise ukusebenzisa iyeza emva kokuthatha isidlo sakho sangokuhlwa.

I-dosage yabantu abadala yesifo sokuwa

Unyango kunyango, umthamo wokuqala womlomo yi-150mg ngemini, eyahlulahlulwe kabini okanye kathathu. Njengakwamanye amachiza onyango, ugqirha unokunyusa idosi ukuya kwi-600mgs ngemini kwaye nayo kufuneka yahlulwe ukuba ithathwe kabini okanye kathathu ngemini. Apha ubukhulu bomthamo yi-600mg ngosuku.

Ukusebenza kunye neziphumo zeli chiza zonke zixhomekeke kumthamo wechiza. Akukho sifundo singqine ukubaluleka kokudibanisa iPregabalin kunye ne-gabapentin. Nangona kunjalo, ugqirha wakho uya kukucebisa ngakumbi malunga namachiza oza kuwasebenzisa kunye neli chiza.

I-Fibromyalgia idosi yabantu abadala

Apha idosi yokuqala yi-75mg ithathwe kabini ngemini kwaye inokulungiswa kwi-150mg kabini ngosuku kwiveki yokuqala yethamo. Umthamo unokunyuswa ngakumbi kwi-225mg ukuba ithathwe kabini ngemini. Elona nani liphezulu le-fibromyalgia yi-450mgs kunye nomthamo wolondolozo malunga ne-300mg ukuya kwi-450mg. Ngakolunye uhlangothi, izifundo zibonisa ukuba ukuthatha i-600mgs ngemini akuniki zibonelelo zePregabalin ezongeziweyo kodwa kunokubangela iziphumo ezibi kakhulu.

I-Pregabalin yentlungu yeNeuropathic

Idosi yokuqala yi-75mg ngosuku kwaye inokunyuswa ibe yi-150mg ngemini. Kwimeko, emva kwethamo leeveki ezimbini okanye ezintathu, akukho phuculo lubalulekileyo, ke amayeza akho anokuyihlenga-hlela ukuya kwi-300mgs. Umthamo wokucetyiswa weSondlo ophakathi kwe-150 ukuya kwi-600mg imithamo eyahlulahlulwe ngosuku.

Isikhokelo esiphezulu kwiDihydroboldenone / iDHB yoKwakha

5.Iziphumo zePregabalin

Kwilizwe lezonyango, kuyacaca ukuba iPregabalin ihambisa iziphumo ezisemgangathweni kunye nezomtsalane kubasebenzisi abalandela imiyalelo yedosi. Ukusukela kokuqala kuvunywa ichiza kwi-2004, izigidi zezigulana zizuze lukhulu kwiPregabalin ingakumbi ekuphathweni kweentlungu zesifo sezinzwa ngenxa yezifo ezahlukeneyo ezinje ngee-Epilepsy, i-post-herpetic neuralgia okanye iintlungu ezenzeka emva koshingles, isifo se-neuropathy esibuhlungu se-neuropathy kunye ne-Fibromyalgia. Kuxhomekeka kwindlela umzimba wakho ojongana ngayo nePregabalin, ungalindela ukonwabela isiphumo sakho ngexesha elifutshane kakhulu.

Iintsuku zokuqala zedosi zinika ugqirha wakho ithuba lokuvavanya inkqubela phambili yakho ngaphambi kokuthatha isigqibo malunga nokulungelelanisa umthamo ezantsi okanye ngaphezulu. Izifundo zibonakalisa ukuba ulindele iziphumo kwiintsuku ezimbalwa zokuqala zedosi. I-Pregabalin sisiyobisi esisebenza ngokukhawuleza, kwaye ke, kufanelekile, ulindele ukuba iintlungu zikhululeke ngaphakathi kwiintsuku zokuqala zedosi. Kwimeko apho ungafumani naluphi na uphuculo kwiveki yokuqala yokuthatha idosi yakho, yazisa ugqirha wakho ukuba alungelelanise umthamo weziphumo ezilungileyo. Imizimba yabantu yahlukile, kwaye ayizenzekeli ukuba ufumane iziphumo ngokukhawuleza njengoko abanye beza kwenza. Ngokuxhomekeke kwimeko yokuba uphantsi kweyeza, iziphumo ziya kwahluka. Ezinye zezinto eziqhelekileyo Iziphumo zePregabalin zibandakanya;

Iyanciphisa iintlungu

I-Pregabalin sisiyobisi esinamandla xa kufikwa ekunciphiseni iintlungu ezibangelwa ngumonakalo we-nerve njenge-peripheral diabetesic neuropathy, chemotherapy-indened neuropathic pain, okanye i-Fibromyalgia. Izifundo ezahlukeneyo zibonisa ukuba iPregabalin lelona chiza lisebenzayo ekunciphiseni iintlungu zekhefu. Isongezo sihlala sisebenza xa sisodwa okanye nokuba sidityaniswe nezinye izinto zonyango.

Ukuphucula ubomi bomgangatho kwizigulana ezineFibromyalgia

Njengoko bekutshiwo ngaphambili, i-Fibromyalgia yimeko apho ufumana khona ukubakho kwentlungu ebanzi. Iimpawu zayo zibandakanya ukungalali kakuhle, ukudinwa, ixhala, uxinzelelo, ukudibana kunye nokuqina kwemisipha. Eli chiza linceda izigulana ukulawula zonke ezi ziphumo.

Iyanciphisa impawu ze-Epileptic

I-FDA ivume uPregabalin (148553-50-8) ukunyanga isifo sokuwa. Eli chiza linconyelwa abaguli abanesifo sokuwa okwethutyana ngenxa yokulimala kwengqondo. Ikwasetyenziswa njengonyango lokudibanisa kwabantu ukuba amanye amayeza okulwa isifo sephepha asilensekile ukusebenza.

Unyango loxinzelelo

Nangona eUnited States yaseMelika, iPregabalin ayisetyenziselwa ukwehlisa amanqanaba enkxalabo, eYurophu, iyeza libonakalise ukuba sisisombululo esihle kakhulu. I-Pregabalin kuthiwa isetyenziselwa i-lab-off ukunceda kunyango lwexhala lokuphazamiseka kwiindawo ezahlukeneyo zehlabathi. Kukho ezinye iimeko ezingabhaliswanga xa ugqirha wakho enokukufumanisa kunyanzelekile ukuba ayalele iPregabalin kwaye azise iziphumo ezisemgangathweni. Zombini ezi zifundo zexesha elifutshane kunye nezethuba elide lonyango zibonisa ukuba eli chiza linokunyanga ngokuphumelelayo ukuba nexhala elinobunkunkqele kubantu abakhulu ngakumbi.

Imfihlo yomgangatho weziphumo zePregabalin kukubandakanya ugqirha wakho kwinkqubo yonke yethamo. Musa ukulungelelanisa umthamo wePregabalin ngaphandle kokuchazela iyeza lakho. Kangangoko unokuthenga ngokulula isiyobisi kwiivenkile ezahlukeneyo ezikwi-Intanethi, ungaqali ukusithatha ngaphandle kokuya kuvavanyo lwezonyango. Eli chiza sele linamandla ekuncedeni iintlungu ezibangelwa zizizathu ezahlukeneyo. Abanye iimbaleki basebenzisa iPregabalin ukulawula iintlungu zemisipha, kunye neentlungu zomgogodla, eziqhelekile ngenxa yokusebenza ngamandla nokhuphiswano.

6.I-Pregabalin isiqingatha sobomi

Esi sisidakamizwa esikhawulezayo esisebenzayo esisebenzayo I-Pregabalin isiqingatha sobomi yeeyure ze-6. Ke ngoko, kwiziphumo ezingcono zePregabalin, iidosi kufuneka zahlulwe kubini okanye ezintathu ngemini. Ukuba sisiyobisi somlomo, kwenza ukuba kube lula kuwe ukufumana iziphumo kuba unesiphelo esifutshane sobomi. Ngalo lonke ixesha khumbula ukunamathela kwimiyalelo yemithamo enikezwe ngugqirha. Nokuba uthatha eyona dosage iphantsi okanye iphakamileyo, isiqingatha sobomi beli chiza lihlala lifana.

Yonke into omele uyazi ngePregabalin

7.Iziphumo ebezingalindelekanga zePregabalin

Njengamanye nje amachiza kwintengiso namhlanje, iPregabalin inokukwazisa nangeziphumo ebezingalindelekanga ezimbi ukuba uyisebenzisa kakhulu. Uninzi lwe Iziphumo ebezingalindelekanga zePregabalin Kungenxa yokusetyenziswa gwenxa okanye ngamanye amaxesha xa inkqubo yakho yomzimba iphikisana kakubi neyeza. Yiloo nto kusoloko kucetyiswa ukuba uqale ngeedosi ezisezantsi, ezinokuthi emva koko zihlengahlengiswe ziinkqubo zakho zonyango emva kokujonga indlela umzimba wakho ophendula ngayo kunyango. Ezinye zeziphumo ebezingalindelekanga zePregabalin zibandakanya;

  • Isiyezi-ngamanye amaxesha usenokufumana ukozela ngelixa uthatha eli chiza, kodwa kufuneka litshabalale emva kwexesha elithile.
  • Ukuqunjelwa, umlomo owomileyo, kunye nentloko ebuhlungu yenye yeziphumo ezibi ngokubanzi onokuthi ube nazo xa usela eli chiza.
  • Abasebenzisi abaninzi bePregabalin bakwakhalaza ngokutya okwandayo, okuthi kamva kukhokelele ekufumaneni ubunzima.
  • Kukho iimeko zokunqongophala kokulungelelaniswa kwemisipha, iingxaki zokuthetha, kunye nokungabikho komzimba olungeleleneyo.

Zonke ezi ziphumo ebezingalindelekanga zePregabalin ziyanyamalala emva kwexesha elithile, kodwa kwimeko yokuba zihlale ixesha elide kunokuba kulindelwe, kuya kufuneka uxelele ugqirha wakho ukuba akuncede ufumane isisombululo ngaphambi kokuba imeko ibe mandundu. Kwelinye icala, kukho iziphumo ebezingalindelekanga ezinobuzaza zokuba uqhagamshele amayeza akho ngoko nangoko kokuba uqalise ukuwafumana, kwaye zibandakanya;

  • Iingxaki zombono, mzuzu uqala ukubona umbono ophindwe kabini, okanye umbono oqaqambileyo okanye naluphi na utshintsho kwamehlo akho ungathandabuzi, tsalela ugqirha wakho kwangoko.
  • Ukudumba kobuso, imilebe yomlomo, amehlo, umqala, ulwimi, intamo, okanye amatyala entloko kufuneka kuxelwe kwangoko.
  • Ezinye iziphumo ebezingalindelekanga ezinzima zibandakanya; iibhulukhwe, ukucheba, ukudumba kwamanqatha, imilenze engezantsi, izandla neengalo okanye iintlungu zesifuba.

Iindaba ezimnandi zezokuba zonke ezi ziphumo zisemngciphekweni wePregabalin zinokulawulwa ukuba wazisa ugqirha wakho ngexesha nangona ezinye iimeko ziya kunyamalala kunye nexesha xa ufumana iziphumo eziphambili ezichazwe apha ngasentla ungaqhubeki nokuthatha umthamo ngaphandle kokuzazisa ngamayeza akho. Ugqirha wakho unokugqiba ekubeni ayeke umthamo ukuba imeko ayilawuleki okanye unokucebisa ngenye indlela, amayeza akhuselekileyo kuwe.

8.Izibonelelo zePregabalin

Eli sisiyobisi esiye sazibonakalisa ukuba siphakathi kweyona chiza inamandla yokulwa i-epileptic kurhwebo namhlanje. Isetyenziselwe ukunciphisa iintlungu ze-neuropathic kwihlabathi liphela, kwaye kwezinye iindawo ezifana neYurophu, kwavunywa kunyango lwexhala. Zininzi izibonelelo oyaonwabela xa uthatha eli chiza, Izibonelelo zePregabalin zezi zilandelayo:

Yenza iziphumo ezisemgangathweni

Izifundo zonyango zibonakalise ukuba iPregabalin ibonelela ngeziphumo ezisemgangathweni kubo bonke abasebenzisi bayo abalandela imiyalelo yedosi. Kulabo bayisebenzisela iintlungu ze-neuropathic, unokufumana ukuphuculwa kwasemva kokuba uthathe idosi yakho yokuqala. Kwiveki yokuqala, kuya kufuneka uqale ngokufumana iziphumo, kwaye oko kunika abezonyango ithuba lokuvavanya inkqubo yamayeza. Akunandaba nokuba kutheni usebenzisa iPregabalin, iziphumo zihlala zinomtsalane.

Isiyobisi somlomo

I-Pregabalin ilawulwa ngomlomo, kwaye ke, akukho zijojo zichaphazelekayo. Ke, isebenza njengeyona nyango ilungileyo yabasebenzisi abangakhuselekanga ngenaliti rhoqo. Akunyanzelekanga ukuba ube nexhala malunga naziphi na iintlungu, kwaye ungahambela ngokulula eli chiza kunye namanye amayeza lo gama usazisa ugqirha wakho.

Inobomi obude obu sisiqingatha

Xa kuthelekiswa namanye amayeza omlomo, i-Pregabalin inobomi obude obusebenzayo kwinkqubo yomzimba wakho, okuqinisekisa ngeziphumo eziqinisekileyo kunye nomgangatho. Kuxhomekeka kwimeko ophatha ngayo eli chiza, uyakufuna kuphela ukuthatha idosi yakho kangangezihlandlo ezibini okanye ezintathu ngosuku kwaye ngamanye amaxesha kube kanye ngemini emva kwesidlo sangokuhlwa.

Ifikeleleka ngokulula

Unako lula Thenga umgubo wePregabalin ngobuninzi okanye yanele nje ukuba umjikelo wakho wethamo usuka kwiivenkile ezahlukeneyo ze-intanethi okanye ikhemisi ekufutshane kuba isemthethweni kwiindawo ezininzi zehlabathi. Ugqirha wakho uya kuba ngumntu olungileyo ukukubonisa ukuba uza kuyithenga phi. Oku kwenza ukuba kube lula kuwe ukuba uthenge kwaye ulisebenzise ichiza ngaphandle koloyiko lokungqubana nomthetho.

Iziphumo ebezingalindelekanga ezimbi

I-Pregabalin ikwazisa ukuba ube neziphumo ebezingalindelekanga ezimbi kakhulu xa kuthelekiswa nezinye i-anticonvulsants. Uya kufumana kuphela iziphumo ebezingalindelekanga ezinjengentloko, ukugabha, phakathi kwezinye iintsuku zokuqala zedosi, kwaye ziya kunyamalala. Ngakolunye uhlangothi, ukuba wazisa ugqirha wakho kwangoko ngokwaneleyo, iziphumo eziphezulu zinokulawulwa ngokulula. Nangona kunjalo, kumava angcono, qiniseka ukuba ungasebenzisi okanye wenze naluphi na uhlengahlengo lwethamo ngaphandle kokuazisa ugqirha wakho.

9.Uhlolo lwePregabalin

Ukujonga uphononongo olwahlukeneyo lwePregabalin, kucacile ukuba abasebenzisi abaninzi banelisekile ziziphumo abazifumanayo emva kokuthatha iyeza. I-Pregabalin isetyenziswa rhoqo njengechiza lokunciphisa iintlungu, kwaye ifumene ingxelo entle evela kubasebenzisi abaninzi. Abaphandi bezonyango baphinde bafaka iziphumo ezahlukileyo, kwaye yiyo loo nto i-FDA ivume ukuba isetyenziswe kunyango lwe-Epilepsy, ne-post-herpetic neuralgia okanye kubuhlungu obuvela emva koshingles, iswekile ye-neuropathy ye-neuropathy kunye ne-Fibromyalgia.

Kweminye imimandla yehlabathi njengaseYurophu, iPregabalin ivunyiwe kunyango lwexhala phakathi kwabantu abadala. Nangona kunjalo, zikho iimeko ezimbalwa ezichaziweyo apho abanye abasebenzisi baye banamava amabi ngechiza. Iziyobisi zisebenza ngendlela eyahlukileyo ngemizimba yabantu, kwaye ayizenzekeli kuba isebenza kuwe kuba inceda umhlobo wakho. Ezinye iimeko zeziphumo ezibi zokuchaphazeleka zibangelwa kukusela ngokugqithisileyo kunye nokusetyenziswa gwenxa kwePregabalin.

Isishwankathelo, esi sisiyobisi esikhulu xa sisetyenziswe ngokuchanekileyo kunye nangezizathu ezifanelekileyo. Incede izigidi zabantu abaphethwe zizifo ezahlukeneyo, njengoko kuboniswe ngasentla. Njengalo naliphi na elinye ichiza eligunyazisiweyo, awuzukuthatha iPregabalin ngaphandle kokuba ugqirha wakho uyacebisa. Kwimeko apho ufumana iziphumo ebezingalindelekanga yazisa ugqirha wakho kwangoko ukukunceda woyise.

Yonke into omele uyazi ngePregabalin

10.I-Pregabalin iyathengiswa

Umhlaba uyatshintsha, kwaye namhlanje, unako bathenge i-Pregabalin powder kwi-intanethi kwiqonga lethu ngexabiso elifikelelekayo. Iwebhusayithi yethu iyasebenziseka lula, isenza kube lula kuwe ukuqhuba usuka kwenye imveliso uye kwenye kunye nokwenza iodolo yakho ngemizuzwana. Unokufikelela kwiwebhusayithi yethu nge-smartphone yakho, ithebhulethi, okanye ikhompyuter yakho. Ngaphezulu koko, senza uhlangulo kwihlabathi liphela kwaye ngexesha elifutshane kakhulu. Ungathenga iPregabalin ngobuninzi okanye nokuba yanele nje kumjikelo wakho wethamo.

Siphambili kumthengisi wePregabalin kwingingqi, kwaye amaxabiso ethu anokungabeki umgangatho weemveliso zethu. Sinikezela ngeemveliso ezahlukeneyo zonyango ezisemgangathweni kwivenkile yethu ekhompyuter. Nangona kunjalo, sihlala sicebisa bonke abathengi bethu ukuba baqiniseke ukuba bangeniswa kunyango ngaphambi kokuba baqale ukuthatha iimveliso zethu. Iimveliso zethu zonyango zinokukhokelela kwiziphumo ebezingalindelekanga xa zisetyenziswe gwenxa okanye zisetyenziswe ngokweqile. I-Pregabalin iyathengiswa Ikwafumaneka kwikhemesti ekufutshane kodwa qiniseka ukuba uyifumana kumthengisi onokwethenjelwa. Ayizizo zonke iivenkile ezikwi-Intanethi okanye ezomzimba ezibonelela ngemveliso esemgangathweni.

11.I-Pregabalin yokunyanga iintlungu kunye nexhala

Kwiminyaka emininzi ngoku, i-Pregabalin ibalulekile kwilizwe lonyango ngakumbi kunyango lweentlungu zesifo, esaziwa ngokuba yintlungu ye-neuropathic. Eli chiza lisebenza ngokulawula iikhemikhali zobuchopho ezithumela imiqondiso kwiiseli zakho, zona ke zinciphise inqanaba leentlungu kwinkqubo yakho yomzimba. E-United States yaseMelika i-FDA ivume iPregabalin kunyango lweentlungu zamazinyo ezibangelwa zizifo ezahlukeneyo ezinje nge-Epilepsy, Fibromyalgia, ne-post-herpetic neuralgia okanye iintlungu ezenzeka emva koshingles kunye nentlungu yeswekile yeswekile.

Nangona kunjalo, i-Pregabalin (148553-50-8) ayivunyelwanga unyango lwexhala e-US, nangona kukho iingxelo zokuba abanye abasebenzisi bayisebenzisa ngaphandle kwelebheli ukulawula imeko. Kwezinye iindawo zehlabathi njengaseYurophu, iPregabalin yamkelwe kunyango loxinzelelo kubantu abadala. Kukho neengxelo ezingangqiniswanga zokuba iPregabalin inokusetyenziswa ukulawula ukudakumba. Ngolwazi oluthe kratya malunga nePregabalin, nxibelelana nodokotela wakho okanye uqhagamshelane nosokhemesti wakho.

Ucaphulo

I-Kim, i-SC, i-Landon, i-JE, kunye noSolomon, i-DH (2013). Iimpawu zeklinikhi kunye nokusetyenziswa kwamayeza phakathi kwezigulana ze-fibromyalgia ezisandula ukumiselwa i-amitriptyline, duloxetine, gabapentin, okanye i-pregabalin. Ukhathalelo lwamayeza kunye nophando, 65(11), 1813-1819.

Umhle, CW, & Brett, AS (2017). UGabapentin kunye ne-pregabalin yentlungu-iyonyuka ichaza isizathu sokuxhalaba? I-New England Journal of Medicine, 377(5), 411-414.

Lam, DM, Choi, SW, Wong, SS, Irwin, MG, & Cheung, CW (2015). Ukusebenza kwePregabalin kwintlungu ye-postoperative yokomelela phantsi kweendidi ezahlukeneyo zokuhlinzwa: uhlalutyo lwe-meta. iyeza, 94(46).

Baldwin, DS, Ajel, K., Masdrakis, VG, Nowak, M., & Rafiq, R. (2013). I-Pregabalin yonyango lwexhala lokuphazamiseka ngokubanzi: uhlaziyo. Isifo se-Neuropsychiatric kunye nonyango, 9, 883.